Around the Web - May 10, 2008

May 10, 2008

Linkfest

Multimedia & Presentations

Blogspotting

  • Greg Linden - This one is from the archives and for all of you interested in computer science, personalized search etc

Self Assembly

Once again, life is very hectic, so not much to report. Follow me on Friendfeed, twitter or check out the Tumblelog, where I am have been putting up some cool stuff lately

Around the web - May 4, 2008

May 4, 2008

It’s been a while, so will jump right into it.

Linkfest

Multimedia & Presentations

Blogspotting

Events

Self Assembly

Not much really. Had fun at Bio-IT World, which is the perfect conference for me, a place where I can combine work with subjects (and hardware) that really get me excited. Someday, Bio-IT World will be a mix of the current Bio-IT, Web 2.0 Expo and Gnomedex; a gathering of minds and industry folk.

I do have my macbook pro now and wishing I hadn’t taken the bad Windows/Dell detour late last year.

New business models for life science content

April 28, 2008

Let me start of by pointing everyone to the standard disclaimer.

Now to the good stuff. I have blogged about NextBio in the past. A couple of weeks about I was on the site and noticed that I could use the search engine without having to log in and get some pretty interesting results fast (well presented, well laid out, etc). I also registered and got an account for enhancements to the search experience. So when I got an advance copy of a press release announcing the formal public launch of the NextBio search engine. From the release

Using NextBio, any researcher or clinician can search the world’s public life sciences data and literature - over 10,000 experiments, 16 million articles, and literally billions of data points. Moreover, users can import their own experimental data into the NextBio search engine, share it with the community, and collaborate with others as never before

The release offers more details. There are over a billion data points, tens of thousands of study results and millions of scientific articles. There is a really neat autocomplete feature. Perhaps most importantly one can make correlations across six species, comparing animal models to human data.

Here are some screenshots. What I like most about the service is just the look and feel, very “Googley” if I might say.

NextBio autocomplete

BRCA2 - NextBio

For me the more interesting part is the business model. The NextBio model is essentially the freemium model that so many have advocated. They offer a quality free search engine, but revenues are going to be driven by commercial services, both hosted search and local installs. Transinsight, with GoPubMed, is doing something similar albeit not quite at this scale.

I like the direction life science content is taking. It’s only going to be better for science and for the companies working in this space

Hopefully I will get a chance to see the presentation tomorrow here at Bio-IT World. Check the site out, I would love to hear what all of you think.

Further readingh
Searching biological information at NextBio

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Your personal health: The Personal Genome

April 24, 2008

An image of a 1901 examination in the faculty of medicine.Last evening, I had a chance to attend an interesing panel discussion on The Personal Genome. The Symposium featured Eric Lander, George Church, Leena Peltonen and Bill Gates and was moderated by Maynard Olson.

My take away from the discussion, which was fueled by questions submitted by the audience and via the web, was that there is so much uncertainty at this time. We know so much, yet so little. At some level, we do not understand the implications of what we know, ethical and medical, at the same time, we underestimate the ability of our own genetics to withstand changes.

Perhaps one of the things that jumped out at me was the general popular belief (which is hardly surprising) that it is a gene or a few genes that can be altered or fixed to address a “problem”. We’re just beginning to grasp the relevance of pathways, of epigenetics, etc, so the long term implications of what we know (and don’t) are still a little fuzzy.

I didn’t get a chance to record or take notes, but I was Twittering the whole thing. Unfortunately, I forgot to use a hashtag, which was silly. Much of the backchannel discussion was on the subject of designer babies. Leena Peltonen made some good points about the impact of genetic selection (we will not be able to alter germ lines), and whether it was desirable from the evolutionary perspective. George Church pointed out that people were going to do it anyway, much as they do today for sex selection or during IVF.

Bill Gates had an interesting opinion on the question of what a personal genome really means. He differentiated between an individual with money getting themselves genotyped or sequenced and between the ability to sequence individuals cheaply and in large quantities. The latter for him was much more important since it will help advance science and medicine. He is quite right of course, and it will be interesting to see how the ability to sequence individuals cheaply has an impact on research and clinical studies, where, in theory, in a few years it will be possible to just sequence everyone.

More on Sandra Porter’s blog

Image via Wikipedia

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Around the web - April 19, 2008

April 20, 2008

Linkfest

Multimedia

Blogspotting

Events

Self Assembly

Well, you’ve already heard about my appearance on Jon Udell’s podcast. Probably one of the highlights of recent times.

I’m still recording the bbgm daily on a nearly daily basis. We’ve also got a thriving bio community these days on Twitter and Friendfeed

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